Blar i forfatter "Valle, Per Christian"
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Colonic distribution of FMT by different enema procedures compared to colonoscopy – proof of concept study using contrast fluid
Skjevling, Linn; Hanssen, Hege Marie; Valle, Per Christian; Goll, Rasmus; Juul, Frederik Emil; Arlov, Øystein; Johnsen, Peter Holger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-23)Background Fecal microbiota transplantation (FMT) has become an important treatment method in recurrent Clostridioides difficile infections and is under investigation as a treatment for several other diseases. FMT’s mechanism of action is assumed to be through alterations of the colon microbiota. FMT can be delivered by several methods, but few studies have directly compared how FMT is distributed ... -
A comparison of Health Related Quality of Life in nurse-led versus conventional Inflammatory Bowel Disease follow-up.
Alvestad, Line; Jelsness-Jørgensen, Lars-Petter; Goll, Rasmus; Clancy, Anne; Valle, Per Christian; Broderstad, Ann Ragnhild (Conference object; Konferansebidrag, 2018) -
Dyspepsia in the young adult patient: Management strategies in the era of declining Helicobacter pylori prevalence and increasing antimicrobial resistance
Valle, Per Christian (Doctoral thesis; Doktorgradsavhandling, 2013-06-21)Helicobacter pylori (H. pylori) is the main cause of peptic ulcer disease (PUD), followed by regular consumption of non-steroidal anti-inflammatory drugs (NSAIDs). The occurrence of gastric cancer is very low below the age of 45-50 years and thus does not justify any kind of symptom-based endoscopic screening. H. pylori also plays a well-documented, but minor role in functional dyspepsia (FD). In ... -
The effect of fecal microbiota transplantation on IBS related quality of life and fatigue in moderate to severe non-constipated irritable bowel: Secondary endpoints of a double blind, randomized, placebo-controlled trial
Johnsen, Peter Holger; Hilpüsch, Frank; Valle, Per Christian; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-23)<i>Background</i> - Severity in irritable bowel syndrome (IBS) is associated to impaired quality of life and fatigue. Fecal microbiota transplantation (FMT) induces significant relief in gastro-intestinal related complaints. The objective was to evaluate the effect of FMT on the secondary endpoints: IBS-related quality of life and fatigue in patients with non-constipated IBS.<p><p> <i>Method</i> ... -
The effect of referral templates on out-patient quality of care in a hospital setting: a cluster randomized controlled trial
Wåhlberg, Henrik; Valle, Per Christian; Malm, Siri; Hovde, Øistein; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-07)<p><i>Background - </i>The assessment of quality of care is an integral part of modern medicine. The referral represents the handing over of care from the general practitioner to the specialist. This study aimed to assess whether an improved referral could lead to improved quality of care. <p><i>Methods - </i> A cluster randomized trial with the general practitioner surgery as the clustering unit ... -
Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiome
Goll, Rasmus; Johnsen, Peter Holger; Hjerde, Erik; Diab, Joseph; Valle, Per Christian; Hilpüsch, Frank; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-29)Irritable bowel syndrome (IBS) is a common disorder of the lower gastrointestinal tract. The pathophysiology is far from settled, but a gut microbial dysbiosis is hypothesized to be a contributing factor. We earlier published a randomized double-blind placebo-controlled clinical trial on fecal microbiota transplantation (FMT) for IBS – the REFIT trial. The present data set describes the engraftment ... -
Health-related quality of life in inflammatory bowel disease: a comparison of patients receiving nurse-led versus conventional follow-up care
Alvestad, Line; Jelsness-Jørgensen, Lars-Petter; Goll, Rasmus; Clancy, Anne Mary Gerard; Gressnes, Thomas; Valle, Per Christian; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-31)Background - Inflammatory bowel disease (IBD), consisting of Crohn's disease (CD) and ulcerative colitis (UC), is a chronic disorder with a considerable negative impact on health-related quality of life (HRQoL). During the past decade, IBD nurse specialists have been increasingly involved in follow-up care of IBD outpatients, in a consultative and coordinating role, closely cooperating with ... -
Impact of referral templates on the quality of referrals from primary to secondary care: a cluster randomised trial
Wåhlberg, Henrik; Valle, Per Christian; Malm, Siri; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-29)Background: The referral letter is an important document facilitating the transfer of care from a general practitioner (GP) to secondary care. Hospital doctors have often criticised the quality and content of referral letters, and the effectiveness of improvement efforts remains uncertain. <p>Methods: A cluster randomised trial was conducted using referral templates for patients in four diagnostic ... -
Integrating the clinical pharmacist into the emergency department interdisciplinary team: A study protocol for a multicentre trial applying a non-randomised stepped-wedge study design
Vesela, Renata; Elenjord, Renate; Lehnbom, Elin; Ofstad, Eirik Hugaas; Johnsgård, Tine; Zahl-Holmstad, Birgitte; Risør, Torsten; Wisløff, Torbjørn; Røslie, Lars; Filseth, Ole Magnus; Valle, Per Christian; Svendsen, Kristian; Frøyshov, Hanne Mathilde; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)Introduction: The ‘emergency department (ED) pharmacist’ is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations. In Norway, few EDs are equipped with ED pharmacists, and research describing effects on patients has not been conducted. The aim of this study is to investigate the impact ... -
Integrating the clinical pharmacist into the emergency department interdisciplinary team: a study protocol for a multicentre trial applying a non-randomised stepped-wedge study design
Vesala, Renata; Elenjord, Renate; Lehnbom, Elin; Ofstad, Eirik Hugaas; Johnsgård, Tine; Zahl-Holmstad, Birgitte; Risør, Torstein; Wisløff, Torbjørn; Røslie, Lars; Filseth, Ole Magnus; Valle, Per Christian; Svendsen, Kristian; Frøyshov, Hanne Mathilde; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)Introduction - The ‘emergency department (ED) pharmacist’ is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations. In Norway, few EDs are equipped with ED pharmacists, and research describing effects on patients has not been conducted. The aim of this study is to investigate the impact of ... -
Practical health co-operation-the impact of a referral template on quality of care and health care co-operation: study protocol for a cluster randomized controlled trial
Wåhlberg, Henrik; Valle, Per Christian; Malm, Siri; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: The referral letter plays a key role both in the communication between primary and secondary care, and in the quality of the health care process. Many studies have attempted to evaluate and improve the quality of these referral letters, but few have assessed the impact of their quality on the health care delivered to each patient. Methods: A cluster randomized trial, with the general ... -
Randomised, placebo-controlled, double-blinded trial of fecal microbiota transplantation in severe obesity: a study protocol
Valle, Per Christian; Skjevling, Linn; Johnsen, Peter Holger; Fjellstad, Maria Serafia; Almå, Kristin Helen; Kulseng, Bård Eirik; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)Introduction - Obesity is one of the main threats to public health in western countries and increases the risk of several diseases, overall morbidity and mortality. Sustained weight loss will reduce risk factors and improve several obesity comorbidities. Options are conservative treatment such as lifestyle changes, bariatric surgery or medications. Conservative treatment has a low success rate, and ... -
Randomised, placebo-controlled, double-blinded trial of fecal microbiota transplantation in severe obesity: a study protocol
Hanssen, Hege Marie; Fjellstad, Maria Serafia; Skjevling, Linn; Johnsen, Peter Holger; Goll, Rasmus; Almå, Kristin Helen; Kulseng, Bård Eirik; Valle, Per Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)Introduction - Obesity is one of the main threats to public health in western countries and increases the risk of several diseases, overall morbidity and mortality. Sustained weight loss will reduce risk factors and improve several obesity comorbidities. Options are conservative treatment such as lifestyle changes, bariatric surgery or medications. Conservative treatment has a low success rate, and ...